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DNA Damage, Repair and Photoadaptation in a Xiphophorus Fish Hybrid

28 Jul 2009

Abstract excerpt

Exposure to sunlight is responsible for most cutaneous malignant melanomas in the human population. It is very likely that DNA damage is an initial event in melanomagenesis, however, the role played by this damage is an open question. To this end, we used a hemipigmented F(1) hybrid of the fish genus Xiphophorus and HPLC tandem mass spectrometry to examine the effects of melanin on the induction and repair of the...

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PMID: 19656328
DOI: 10.1111/j.1751-1097.2009.00591.x

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