Article
Common variants associated with blood lipid levels do not affect carotid plaque composition.
Atherosclerosis - 1 Sept 2015
Siemelink M A, van der Laan S W, van Setten J, de Vries J P P M, de Borst G J, Moll F L, den Ruijter H M, Asselbergs F W, Pasterkamp G, de Bakker P I W
Abstract excerpt
INTRODUCTION: Although plasma lipid levels are known to influence the risk of cardiovascular disease (CVD), little is known about their effect on atherosclerotic plaque composition. To date, large-scale genome-wide association studies have identified 157 common single-nucleotide polymorphisms (SNPs) that influence plasma lipid levels, providing a powerful tool to investigate the effect of plasma lipid levels on...
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