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Article

Associations of PPARGC1A haplotypes with plaque score but not with intima-media thickness of carotid arteries in middle-aged subjects.

Stroke - 1 Sept 2006

Iglseder Bernhard, Oberkofler Hannes, Felder Thomas K, Klein Kerstin, Paulweber Bernhard, Krempler Franz, Tregouet David A, Patsch Wolfgang

Abstract excerpt

BACKGROUND AND PURPOSE: Peroxisome proliferator activated receptor gamma coactivator 1alpha (PGC-1alpha, PPARGC1A) integrates the transcriptional program of mitochondrial biogenesis. Mitochondria are the main source of cellular reactive oxygen species implicated in atherogenesis. We therefore asc...

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Source

Identifiers

PMID: 16902166
DOI: 10.1161/01.STR.0000238584.57864.d4

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16902166-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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