Article
Cholesteryl ester transfer protein genetic polymorphisms, HDL cholesterol, and subclinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis.
Atherosclerosis - 1 Oct 2008
Tsai Michael Y, Johnson Craig, Kao W H Linda, Sharrett A Richey, Arends Valerie L, Kronmal Richard, Jenny Nancy Swords, Jacobs David R, Arnett Donna, O'Leary Daniel, Post Wendy
Abstract excerpt
The cholesteryl ester transfer protein (CETP) plays a key role in high-density lipoprotein (HDL) metabolism. Genetic variants that alter CETP activity and concentration may cause significant alterations in HDL-cholesterol (HDL-C) concentration; however, controversies remain about whether these genetic variants are associated with atherosclerosis. We genotyped the CETP R451Q, A373P, -629C/A, Taq1B, and -2505C/A...
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