Article
G-protein genomic association with normal variation in gray matter density.
Human brain mapping - 1 Nov 2015
Chen Jiayu, Calhoun Vince D, Arias-Vasquez Alejandro, Zwiers Marcel P, van Hulzen Kimm, Fernández Guillén, Fisher Simon E, Franke Barbara, Turner Jessica A, Liu Jingyu
Abstract excerpt
While detecting genetic variations underlying brain structures helps reveal mechanisms of neural disorders, high data dimensionality poses a major challenge for imaging genomic association studies. In this work, we present the application of a recently proposed approach, parallel independent component analysis with reference (pICA-R), to investigate genomic factors potentially regulating gray matter variation in...
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