Article
Guided exploration of genomic risk for gray matter abnormalities in schizophrenia using parallel independent component analysis with reference.
NeuroImage - 1 Dec 2013
Chen Jiayu, Calhoun Vince D, Pearlson Godfrey D, Perrone-Bizzozero Nora, Sui Jing, Turner Jessica A, Bustillo Juan R, Ehrlich Stefan, Sponheim Scott R, Cañive José M, Ho Beng-Choon, Liu Jingyu
Abstract excerpt
One application of imaging genomics is to explore genetic variants associated with brain structure and function, presenting a new means of mapping genetic influences on mental disorders. While there is growing interest in performing genome-wide searches for determinants, it remains challenging to identify genetic factors of small effect size, especially in limited sample sizes. In an attempt to address this...
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