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Article

Modeling genotype-protein interaction and correlation for Alzheimer's disease: a multi-omics imaging genetics study.

Briefings in bioinformatics - 22 Jan 2024

Zhang Jin, Ma Zikang, Yang Yan, Guo Lei, Du Lei

Abstract excerpt

Integrating and analyzing multiple omics data sets, including genomics, proteomics and radiomics, can significantly advance researchers' comprehensive understanding of Alzheimer's disease (AD). However, current methodologies primarily focus on the main effects of genetic variation and protein, overlooking non-additive effects such as genotype-protein interaction (GPI) and correlation patterns in brain imaging...

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Identifiers

PMID: 38348747
DOI: 10.1093/bib/bbae038
PMCID: PMC10939371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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