Article

Sparse parallel independent component analysis and its application to identify linked genomic and gray matter alterations underlying working memory impairment in attention-deficit/hyperactivity disorder

2020-07-12

Abstract excerpt

Most psychiatric disorders are highly heritable and associated with altered brain structural and functional patterns. Data fusion analyses on brain imaging and genetics, one of which is parallel independent component analysis (pICA), enable the link of genomic factors to brain patterns. Due to the small to modest effect sizes of common genetic variants in psychiatric disorders, it is usually challenging to reliabl...

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Literature Corpus work: 3405f4be-b7a3-5696-990d-58834a3b672d
DOI: 10.1101/2020.07.11.198622

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