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Article

Common genetic variants and gene expression associated with white matter microstructure in the human brain.

NeuroImage - 15 Aug 2014

Sprooten Emma, Knowles Emma E, McKay D Reese, Göring Harald H, Curran Joanne E, Kent Jack W, Carless Melanie A, Dyer Thomas D, Drigalenko Eugene I, Olvera Rene L, Fox Peter T, Almasy Laura, Duggirala Ravi, Kochunov Peter, Blangero John, Glahn David C

Abstract excerpt

Identifying genes that contribute to white matter microstructure should provide insights into the neurobiological processes that regulate white matter development, plasticity and pathology. We detected five significant SNPs using genome-wide association analysis on a global measure of fractional anisotropy in 776 individuals from large extended pedigrees. Genetic correlations and genome-wide association results...

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Source

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Identifiers

PMID: 24736177
DOI: 10.1016/j.neuroimage.2014.04.021
PMCID: PMC4107465

Genes

CCDC91
GNA13
HTR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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