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Article

Functional role of dimerization and CP190 interacting domains of CTCF protein in Drosophila melanogaster.

BMC biology - 7 Aug 2015

Bonchuk Artem, Maksimenko Oksana, Kyrchanova Olga, Ivlieva Tatyana, Mogila Vladic, Deshpande Girish, Wolle Daniel, Schedl Paul, Georgiev Pavel

Abstract excerpt

BACKGROUND: Insulators play a central role in gene regulation, chromosomal architecture and genome function in higher eukaryotes. To learn more about how insulators carry out their diverse functions, we have begun an analysis of the Drosophila CTCF (dCTCF). CTCF is one of the few insulator proteins known to be conserved from flies to man. RESULTS: In the studies reported here we have focused on the identification...

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Source

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Identifiers

PMID: 26248466
DOI: 10.1186/s12915-015-0168-7
PMCID: PMC4528719

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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