Article
Cooperation between architectural C2H2 proteins in CP190 recruitment to Drosophila regulatory elements.
Epigenetics & chromatin - 24 Dec 2025
Maksimenko Oksana, Klimenko Natalia, Salloum Ghadeer, Umnova Anastasia, Kyrchanova Olga, Melnikova Larisa, Georgiev Pavel
Abstract excerpt
BACKGROUND: CTCF (CCCTC-binding factor) is the best-studied architectural protein that is highly conserved among animals, including Drosophila and mammals. In Drosophila, CTCF is involved in the organization of functional promoters and insulators, in cooperation with many other architectural proteins, including Su(Hw) and Pita. These proteins, like many other architectural proteins, interact with CP190, which,...
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