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Article

The Drosophila homolog of the mammalian imprint regulator, CTCF, maintains the maternal genomic imprint in Drosophila melanogaster.

BMC biology - 30 Jul 2010

MacDonald William A, Menon Debashish, Bartlett Nicholas J, Sperry G Elizabeth, Rasheva Vanya, Meller Victoria, Lloyd Vett K

Abstract excerpt

BACKGROUND: CTCF is a versatile zinc finger DNA-binding protein that functions as a highly conserved epigenetic transcriptional regulator. CTCF is known to act as a chromosomal insulator, bind promoter regions, and facilitate long-range chromatin interactions. In mammals, CTCF is active in the regulatory regions of some genes that exhibit genomic imprinting, acting as insulator on only one parental allele to...

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Identifiers

PMID: 20673338
DOI: 10.1186/1741-7007-8-105
PMCID: PMC2922095

Genes

CTCF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Drosophila homolog of the mammalian imprint regulator, CTCF, maintains the maternal genomic imprint in Drosophila melanogaster.PMID 20673338Read ↗

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