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Epigenetic Regulation of Chondrocyte Catabolism and Anabolism in Osteoarthritis

1 Aug 2015

Abstract excerpt

Osteoarthritis (OA) is one of the most prevalent forms of joint disorder, associated with a tremendous socioeconomic burden worldwide. Various non-genetic and lifestyle-related factors such as aging and obesity have been recognized as major risk factors for OA, underscoring the potential role for epigenetic regulation in the pathogenesis of the disease. OA-associated epigenetic aberrations have been noted at the...

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PMID: 26242192
DOI: 10.14348/molcells.2015.0200

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