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Epigenetics as a Therapeutic Target in Osteoarthritis

21 Jan 2023

Abstract excerpt

Osteoarthritis (OA) is a heterogenous, complex disease affecting the integrity of diarthrodial joints that, despite its high prevalence worldwide, lacks effective treatment. In recent years it has been discovered that epigenetics may play an important role in OA. Our objective is to review the current knowledge of the three classical epigenetic mechanisms-DNA methylation, histone post-translational modifications...

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PMID: 37259307
DOI: 10.3390/ph16020156

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