Article
Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs.
Osteoarthritis and cartilage - 1 May 2012
Barter M J, Bui C, Young D A
Abstract excerpt
Osteoarthritis (OA) is a complex multifactorial disease with a strong genetic component. Several studies have suggested or identified epigenetic events that may play a role in OA progression and the gene expression changes observed in diseased cartilage. The aim of this review is to inform about current research in epigenetics and epigenetics in OA. Epigenetic mechanisms include DNA methylation, histone...
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