Article
Epigenetic Regulation of Chondrocytes and Subchondral Bone in Osteoarthritis
14 Apr 2022
Abstract excerpt
The aim of this review is to provide an updated review of the epigenetic factors involved in the onset and development of osteoarthritis (OA). OA is a prevalent degenerative joint disease characterized by chronic inflammation, ectopic bone formation within the joint, and physical and proteolytic cartilage degradation which result in chronic pain and loss of mobility. At present, no disease-modifying therapeutics...