Article
Role of hormones in cartilage and joint metabolism: understanding an unhealthy metabolic phenotype in osteoarthritis.
Menopause (New York, N.Y.) - 1 May 2013
Bay-Jensen Anne C, Slagboom Eline, Chen-An Pingping, Alexandersen Peter, Qvist Per, Christiansen Claus, Meulenbelt Ingrid, Karsdal Morten A
Abstract excerpt
OBJECTIVE: Joint health is affected by local and systemic hormones. It is well accepted that systemic factors regulate the metabolism of joint tissues, and that substantial cross-talk between tissues actively contributes to homeostasis. In the current review, we try to define a subtype of osteoarthritis (OA), metabolic OA, which is dependent on an unhealthy phenotype. METHODS: Peer-reviewed research articles and...
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