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Article

Mechanism of a flow-gated angiogenesis switch: early signaling events at cell-matrix and cell-cell junctions.

Integrative biology : quantitative biosciences from nano to macro - 1 Aug 2012

Vickerman Vernella, Kamm Roger D

Abstract excerpt

A bias towards angiogenesis from the venous circulation has long been known, but its cause remains unclear. Here we explore the possibility that high interstitial pressure in tumors and the resultant net filtration pressure gradient that would induce flow from the interstitium into the venous cir...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22673733
DOI: 10.1039/c2ib00184e
PMCID: PMC4090039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22673733-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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