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Article

Lower CYP2C9 activity in Turkish patients with Behçet's disease compared to healthy subjects: a down-regulation due to inflammation?

European journal of clinical pharmacology - 1 Oct 2015

Goktaş Mustafa Tugrul, Hatta Fazleen, Karaca Ozgur, Kalkisim Said, Kilic Levent, Akdogan Ali, Babaoglu Melih O, Bozkurt Atilla, Helldén Anders, Bertilsson Leif, Yasar Umit

Abstract excerpt

BACKGROUND: We previously reported on a Swedish patient with Behçet's disease (BD) who was an ultra-rapid metaboliser of drugs catalysed by CYP2C9. Was this extreme metabolism caused by the disease? AIM: This study aims to compare the genotype/phenotype of CYP2C9 in patients with BD and healthy subjects. As the occurrence of BD is high in Turkey, all subjects were recruited from this country. METHODS: Genotyping...

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Share to Behcet Syndrome
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26233334
DOI: 10.1007/s00228-015-1899-7

Genes

CYP2C9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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