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Article

Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.

European journal of clinical pharmacology - 1 Aug 2010

Helldén Anders, Bergman Ulf, Engström Hellgren Karin, Masquelier Michèle, Nilsson Remahl Ingela, Odar-Cederlöf Ingegerd, Ramsjö Margareta, Bertilsson Leif

Abstract excerpt

PURPOSE: The cytochrome P450 enzyme CYP2C9 metabolizes several important drugs, such as warfarin and oral antidiabetic drugs. The enzyme is polymorphic, and all known alleles, for example, CYP2C9*2 and*3, give decreased activity. Ultra-high activity of the enzyme has not yet been reported. METHOD...

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Source

Identifiers

PMID: 20405111
DOI: 10.1007/s00228-010-0820-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20405111-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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