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Article

MDR1 gene polymorphisms may be associated with Behçet's disease and its colchicum treatment response.

Gene - 1 Sept 2012

Rustemoglu Aydin, Gül Ülker, Gümüş-Akay Güvem, Gönül Müzeyyen, Yiğit Serbülent, Bozkurt Nihan, Karadağ Aynur, Pişkin Emine, Sunguroğlu Asuman, Kadıkıran Ahmet

Abstract excerpt

Behçet's disease (BD) is a chronic multisystem disorder. Infectious agents, immune system mechanisms, and genetic factors are implicated in the etiopathogenesis of BD, which remains to be explained. The human MDR1 (ABCB1) gene encoder P-glycoprotein (P-gp) plays a key role in drug disposition, serves as a protective mechanism against xenobiotics, and provides additional protection for the brain, testis, and...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22705826
DOI: 10.1016/j.gene.2012.05.040

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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