Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Polymorphism of CYP2C19 gene in the Stanislas cohort. A link with inflammation.

Annals of human genetics - 1 Mar 2008

Bertrand-Thiébault C, Berrahmoune H, Thompson A, Marie B, Droesch S, Siest G, Foernzler D, Visvikis-Siest S

Abstract excerpt

CYP2C19, a member of the cytochrome P450 family, metabolises arachidonic acid to produce epoxyeicosanoid acids, which are involved in vascular tone and inflammation. Thus, this study describes the possible relationship between a CYP2C19 polymorphism (681G>A) and three inflammatory markers: interleukin (IL)-6, tumor necrosis factor-alpha (TNF-alpha) and high sensitivity C-reactive protein (hs-CRP) in healthy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to C-Reactive Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

Share to Enzyme-Linked Immunosorbent Assay

Share to France

Share to Interleukin-6

Share to Mixed Function Oxygenases

Share to Nephelometry and Turbidimetry

Source

Identifiers

PMID: 18205890
DOI: 10.1111/j.1469-1809.2007.00417.x

Genes

CRP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Polymorphism of CYP2C19 gene in the Stanislas cohort. A link with inflammation.PMID 18205890Read ↗

Role of CYP2C9 and CYP2C19 polymorphisms in patients with atherosclerosis.Semantic proximity Read ↗

Biological variations, genetic polymorphisms and familial resemblance of TNF-alpha and IL-6 concentrations: STANISLAS cohort.Semantic proximity Read ↗

CYP2J2 - regulation, function and polymorphism.Semantic proximity Read ↗

Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases.Semantic proximity Read ↗

The STANISLAS Cohort: a 10-year follow-up of supposed healthy families. Gene-environment interactions, reference values and evaluation of biomarkers in prevention of cardiovascular diseases.Semantic proximity Read ↗

Influence of cytochrome P450 2C9*2 and 2C9*3 variants on the risk of ischemic stroke: a cross-sectional case-control study.Semantic proximity Read ↗

Polymorphisms of CYP2C8, CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population.Semantic proximity Read ↗

A polymorphism in the cyclooxygenase 1 gene is associated with decreased inflammatory prostaglandin F2alpha formation and lower risk of cardiovascular disease.Semantic proximity Read ↗

Association of CYP2C19*2 and *3 genetic variants with essential hypertension in Koreans.Semantic proximity Read ↗

Decreased Activity and Genetic Polymorphisms of CYP2C19 in Behçet's Disease.Semantic proximity Read ↗

Sex differences in the impact of CYP2C19 polymorphisms and low-grade inflammation on coronary microvascular disorder.Semantic proximity Read ↗

Lower CYP2C9 activity in Turkish patients with Behçet's disease compared to healthy subjects: a down-regulation due to inflammation?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.