Article
Genetic susceptibility to interstitial pulmonary fibrosis in mice induced by vanadium pentoxide (V2O5).
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2014
Walters Dianne M, White Kevin M, Patel Ushma, Davis Martin J, Veluci-Marlow Roberta M, Bhupanapadu Sunkesula Solomon Raju, Bonner James C, Martin Jessica R, Gladwell Wes, Kleeberger Steven R
Abstract excerpt
Interstitial lung diseases (ILDs) are characterized by injury, inflammation, and scarring of alveoli, leading to impaired function. The etiology of idiopathic forms of ILD is not understood, making them particularly difficult to study due to the lack of appropriate animal models. Consequently, few effective therapies have emerged. We developed an inbred mouse model of ILD using vanadium pentoxide (V2O5), the most...
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