Article
Synergy of two human endogenous retroviruses in multiple myeloma.
Leukemia research - 1 Oct 2015
Schmidt Kathrine L M, Vangsted Annette J, Hansen Bettina, Vogel Ulla B, Hermansen N Emil U, Jensen Sara B, Laska Magdalena J, Nexø Bjørn A
Abstract excerpt
Multiple myeloma (MM) is a severe, incurable neoplasm of the plasma cells. In this study we have used genetic epidemiology to associate the risk of MM with endogenous retroviral loci in humans. We used SNP analysis on a Sequenom platform and statistical analysis in SPSS. Markers near two endogenous retroviral loci, HERV-Fc1 on chromosome X and HERV-K on chromosome 1, were associated with MM. Moreover, there was...
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