Article
Interactions between SNPs affecting inflammatory response genes are associated with multiple myeloma disease risk and survival.
Leukemia & lymphoma - 1 Nov 2017
Nielsen Kaspar René, Rodrigo-Domingo Maria, Steffensen Rudi, Baech John, Bergkvist Kim S, Oosterhof Liesbeth, Schmitz Alexander, Bødker Julie Støve, Johansen Preben, Vogel Ulla, Vangsted Anette, Dybkær Karen, Bøgsted Martin, Johnsen Hans Erik
Abstract excerpt
The origin of multiple myeloma depends on interactions with stromal cells in the course of normal B-cell differentiation and evolution of immunity. The concept of the present study is that genes involved in MM pathogenesis, such as immune response genes, can be identified by screening for single-nucleotide polymorphisms (SNPs) involved in the immune response and a subsequent statistical analysis that focusses on...
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