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Article

Genetic variations in multiple myeloma II: association with effect of treatment.

European journal of haematology - 1 Feb 2012

Vangsted Annette, Klausen Tobias W, Vogel Ulla

Abstract excerpt

Association studies on genetic variation to treatment effect may serve as a predictive marker for effect of treatment and can also uncover biological pathways behind drug effect. Single-nucleotide polymorphisms (SNPs) have been studied in relation to high-dose treatment (HDT), thalidomide- and bortezomib-based therapy, maintenance treatment with interferon-α and in relation to therapy-related adverse effects...

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Source

Identifiers

PMID: 21883476
DOI: 10.1111/j.1600-0609.2011.01696.x

Genes

MBL2
MPO
NFKB1
NFKB2
TRAF3

Provenance

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