Article
Blood flow and endothelial cell phenotype regulation during sprouting angiogenesis.
Medical & biological engineering & computing - 1 Mar 2016
Bazmara Hossein, Soltani M, Sefidgar Mostafa, Bazargan Majid, Mousavi Naeenian Mojtaba, Rahmim Arman
Abstract excerpt
The role of the endothelial cell environment and shear stress induced by blood flow in phenotype determination and lumen formation has been clearly illustrated in recent studies. In the present work, a model is developed to map environmental and flow induced signals in sprouting angiogenesis to endothelial cell phenotype and lumen formation. To follow the endothelial cell lumen formation, its signaling pathway is...
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