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Article

Test for rare variants by environment interactions in sequencing association studies.

Biometrics - 1 Mar 2016

Lin Xinyi, Lee Seunggeun, Wu Michael C, Wang Chaolong, Chen Han, Li Zilin, Lin Xihong

Abstract excerpt

We consider in this article testing rare variants by environment interactions in sequencing association studies. Current methods for studying the association of rare variants with traits cannot be readily applied for testing for rare variants by environment interactions, as these methods do not effectively control for the main effects of rare variants, leading to unstable results and/or inflated Type 1 error...

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Identifiers

PMID: 26229047
DOI: 10.1111/biom.12368
PMCID: PMC4733434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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