Article
Computational study enlightens the structural role of the alcohol acyltransferase DFGWG motif.
Journal of molecular modeling - 1 Aug 2015
Morales-Quintana Luis, Moya-León María Alejandra, Herrera Raúl
Abstract excerpt
Alcohol acyltransferases (AAT) catalyze the esterification reaction of alcohols and acyl-CoA into esters in fruits and flowers. Despite the high divergence between AAT enzymes, two important and conserved motifs are shared: the catalytic HxxxD motif, and the DFGWG motif. The latter is proposed to play a structural role; however, its function remains unclear. The DFGWG motif is located in loop 21 and stabilized by...
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