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Article

GWAS identifies two susceptibility loci for lamotrigine-induced skin rash in patients with epilepsy.

Epilepsy research - 1 Sept 2015

Jang Hui Won, Kim So Won, Cho Yang-Je, Heo Kyoung, Lee Byung In, Lee Sang Kun, Jang In-Jin, Lee Min Goo, Kim Won-Joo, Lee Ji Hyun

Abstract excerpt

PURPOSE: Lamotrigine (LTG)-induced maculopapular eruption (MPE) often causes treatment discontinuation and rising burdens on current healthcare systems. We conducted a genome-wide association study to identify novel susceptibility loci associated with LTG-induced MPE in patients with epilepsy. MATERIALS AND METHODS: We enrolled patients with LTG-induced MPE (n=34) and utilized the Korea Association Resource...

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Source

Identifiers

PMID: 26220383
DOI: 10.1016/j.eplepsyres.2015.05.014

Genes

TNS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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