Article
Predictive markers for carbamazepine and lamotrigine-induced maculopapular exanthema in Han Chinese.
Epilepsy research - 1 Sept 2013
Li Li-Juan, Hu Fa-Yun, Wu Xin-Tong, An Dong-Mei, Yan Bo, Zhou Dong
Abstract excerpt
The aims of this study were to clarify the possible associations of carbamazepine (CBZ)- and lamotrigine (LTG)-induced maculopapular exanthema (MPE) with the human leukocyte antigen (HLA) alleles in Chinese patients. A total of 249 subjects, including 40 patients with CBZ-induced MPE (CBZ-MPE), 43 patients with LTG-induced MPE (LTG-MPE), 52 CBZ-tolerant controls, 42 LTG-tolerant controls and 72 healthy controls,...
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