Article
HLA-A*02:01:01/-B*35:01:01/-C*04:01:01 haplotype associated with lamotrigine-induced maculopapular exanthema in Mexican Mestizo patients.
Pharmacogenomics - 1 Jan 2014
Fricke-Galindo Ingrid, Martínez-Juárez Iris E, Monroy-Jaramillo Nancy, Jung-Cook Helgi, Falfán-Valencia Ramcés, Ortega-Vázquez Alberto, Alonso-Vilatela María Elisa, López-López Marisol
Abstract excerpt
AIM: Several HLA alleles have been associated with antiepileptic drugs (AEDs)-induced cutaneous adverse drug reactions (cADRs) in different populations; however, this has not been investigated in Mexican Mestizos (MM). Thus, the purpose of this preliminary study was to determine the association of HLA class I alleles with AED-induced cADRs in MM patients. MATERIALS & METHODS: This case-control association study...
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