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The HLA-A2402/Cw0102 haplotype is associated with lamotrigine-induced maculopapular eruption in the Korean population.

Epilepsia - 1 Oct 2015

Moon Jangsup, Park Han-Ki, Chu Kon, Sunwoo Jun-Sang, Byun Jung-Ick, Lim Jung-Ah, Kim Tae-Joon, Shin Jung-Won, Lee Soon-Tae, Jung Keun-Hwa, Jung Ki-Young, Jeon Daejong, Kim Dong Wook, Yu Kyung-Sang, Jang In-Jin, Kang Hye-Ryun, Park Heung-Woo, Lee Sang Kun

Abstract excerpt

The use of lamotrigine (LTG) can be limited by the occurrence of cutaneous adverse drug reactions (cADRs) that range from maculopapular eruption (MPE) to the more severe Stevens-Johnson syndrome and toxic epidermal necrolysis. A few human leukocyte antigen (HLA)-related genetic risk factors for carbamazepine-induced cADR have been identified. However, the HLA-related genetic risk factors associated with...

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Identifiers

PMID: 26282450
DOI: 10.1111/epi.13087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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