Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hla-B alleles and lamotrigine-induced cutaneous adverse drug reactions in the Han Chinese population.

Basic & clinical pharmacology & toxicology - 1 Jul 2011

Shi Yi-Wu, Min Fu-Li, Liu Xiao-Rong, Zan Li-Xuan, Gao Mei-Mei, Yu Mei-Juan, Liao Wei-Ping

Abstract excerpt

Lamotrigine (LTG) is a commonly used antiepileptic drug. However, the use of LTG is limited because of its cutaneous adverse drug reactions (cADRs) ranging from mild maculopapular eruption (MPE) to severe Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). A strong association between HLA-B*1502 and carbamazepine-induced SJS/TEN has been identified in Chinese and Thai. Although three of seven...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticonvulsants
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Drug Eruptions

Share to HLA-B Antigens

Share to Lamotrigine

Share to Triazines

Source

Identifiers

PMID: 21306565
DOI: 10.1111/j.1742-7843.2011.00681.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hla-B alleles and lamotrigine-induced cutaneous adverse drug reactions in the Han Chinese population.PMID 21306565Read ↗

Association study of lamotrigine-induced cutaneous adverse reactions and HLA-B*1502 in a Han Chinese population.Semantic proximity Read ↗

Association between carbamazepine-induced cutaneous adverse drug reactions and the HLA-B*1502 allele among patients in central China.Semantic proximity Read ↗

Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.Semantic proximity Read ↗

The HLA-A*2402/Cw*0102 haplotype is associated with lamotrigine-induced maculopapular eruption in the Korean population.Semantic proximity Read ↗

Association of HLA-B*1502 allele with lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese subjects: a meta-analysis.Semantic proximity Read ↗

HLA-B alleles associated with severe cutaneous reactions to antiepileptic drugs in Han Chinese.Semantic proximity Read ↗

Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study.Semantic proximity Read ↗

Investigating the association of Lamotrigine and Phenytoin-induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with HLA-B*1502 in Iranian population.Semantic proximity Read ↗

Association between HLA-B*1502 allele and carbamazepine-induced severe cutaneous adverse reactions in Han people of southern China mainland.Semantic proximity Read ↗

Association of HLA-A and HLA-B Alleles with Lamotrigine-Induced Cutaneous Adverse Drug Reactions in the Thai PopulationSemantic proximity Read ↗

Genetic predisposition for the development of lamotrigine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis: a systematic review and meta-analysis.Semantic proximity Read ↗

Association between HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in a Thai population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.