Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival

27 Jul 2015

Abstract excerpt

BACKGROUND: The epidermal growth factor (EGF) family of ligands has been implicated in promoting breast cancer initiation, growth and progression. The contributions of EGF family ligands and their receptors to breast cancer are complex, and the specific mechanisms through which different ligands regulate breast tumor initiation and growth are not well-defined. These studies focus on the EGF family member...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibroblast Growth Factor Research
Share to HER2/EGFR in Cancer Research
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26215578
DOI: 10.1186/s12943-015-0408-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survivalPMID 26215578Read ↗

Estrogen receptors and extracellular matrix: the critical interplay in cancer development and progressionSemantic proximity Read ↗

EGR1 and the ERK‐ERF axis drive mammary cell migration in response to EGFSemantic proximity Read ↗

SPARC is a new driver of early breast tumor progression via TGF-β -dependent mechanismSemantic proximity Read ↗

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor ProgressionSemantic proximity Read ↗

The Role of EREG/EGFR Pathway in Tumor Progression.Semantic proximity Read ↗

Epithelial to mesenchymal transition in human breast epithelial cells transformed by 17beta-estradiol.Semantic proximity Read ↗

Intratumoral epiregulin is a marker of advanced disease in non-small cell lung cancer patients and confers invasive properties on EGFR-mutant cells.Semantic proximity Read ↗

Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast CancerSemantic proximity Read ↗

Invasive Lobular Carcinoma Cell Lines Are Characterized by Unique Estrogen-Mediated Gene Expression Patterns and Altered Tamoxifen ResponseSemantic proximity Read ↗

MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 proteinSemantic proximity Read ↗

Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathwaySemantic proximity Read ↗

Identification of Cyclin D1– and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and ProgressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.