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Estrogen receptors and extracellular matrix: the critical interplay in cancer development and progression

16 Sept 2024

Abstract excerpt

Cancer remains a significant global health concern. Breast cancer is a multifaceted and prevalent disease influenced by several factors, among which estrogen receptors (ERs) and the extracellular matrix (ECM) play pivotal roles. ERs, encompassing ERα and ERβ, exert significant diversity on tumor behavior, cell signaling, invasion, and metastatic potential, thus guiding breast cancer prognosis. Understanding the...

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PMID: 39285617
DOI: 10.1111/febs.17270

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