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MMP11 promotes the proliferation and progression of breast cancer through stabilizing Smad2 protein

3 Feb 2021

Abstract excerpt

Breast cancer (BC) is one of the most common malignant tumours in women. The matrix metalloproteinase (MMP) enzyme family plays a complex role in the development of BC. There is increasing evidence that MMP11 plays a major role in BC; however, the underlying mechanisms are not clear. The present study confirmed by analysing clinical samples and TCGA data sets, that high expression of MMP11 in clinical samples of...

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PMID: 33649832
DOI: 10.3892/or.2021.7967

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