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Article

Temporal in vivo platelet labeling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

29 Aug 2022

Abstract excerpt

The proportion of young platelets, also known as newly formed or reticulated, within the overall platelet population has been clinically correlated with adverse cardiovascular outcomes. However, our understanding of this is incomplete because of limitations in the technical approaches available to study platelets of different ages. In this study, we have developed and validated an in vivo temporal labeling...

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PMID: 36037520
DOI: 10.1182/bloodadvances.2022007099

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