Article
Sortin2 enhances endocytic trafficking towards the vacuole in Saccharomyces cerevisiae.
Biological research - 25 Jul 2015
Vásquez-Soto Beatriz, Manríquez Nicolás, Cruz-Amaya Mirna, Zouhar Jan, Raikhel Natasha V, Norambuena Lorena
Abstract excerpt
BACKGROUND: A highly regulated trafficking of cargo vesicles in eukaryotes performs protein delivery to a variety of cellular compartments of endomembrane system. The two main routes, the secretory and the endocytic pathways have pivotal functions in uni- and multi-cellular organisms. Protein delivery and targeting includes cargo recognition, vesicle formation and fusion. Developing new tools to modulate protein...
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