An essential subfamily of Drs2p-related P-type ATPases is required for protein trafficking between Golgi complex and endosomal/vacuolar system.

doi:10.1091/mbc.e02-03-0172

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Article

An essential subfamily of Drs2p-related P-type ATPases is required for protein trafficking between Golgi complex and endosomal/vacuolar system.

Molecular biology of the cell - 1 Sept 2002

Hua Zhaolin, Fatheddin Parvin, Graham Todd R

Abstract excerpt

The Saccharomyces cerevisiae genome contains five genes encoding P-type ATPases that are potential aminophospholipid translocases (APTs): DRS2, NEO1, and three uncharacterized open reading frames that we have named DNF1, DNF2, and DNF3 for DRS2/NEO1 family. NEO1 is the only essential gene in APT family and seems to be functionally distinct from the DRS2/DNF genes. The drs2Delta dnf1Delta dnf2Delta dnf3Delta...

Topics

Adenosine Triphosphatases
Alkaline Phosphatase
Alleles
Biological Transport
Calcium-Transporting ATPases
Carboxypeptidases
Cathepsin A
Endosomes
Glycoside Hydrolases
Golgi Apparatus
Green Fluorescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Luminescent Proteins

Membrane Proteins

Models, Biological

Mutation

Open Reading Frames

Phenotype

Plasmids

Source

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Identifiers

PMID: 12221123
DOI: 10.1091/mbc.e02-03-0172
PMCID: PMC124150

Genes

NEO1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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