Article
A family of small coiled-coil-forming proteins functioning at the late endosome in yeast.
Molecular biology of the cell - 1 Mar 2001
Kranz A, Kinner A, Kölling R
Abstract excerpt
The multispanning membrane protein Ste6, a member of the ABC-transporter family, is transported to the yeast vacuole for degradation. To identify functions involved in the intracellular trafficking of polytopic membrane proteins, we looked for functions that block Ste6 transport to the vacuole upon overproduction. In our screen, we identified several known vacuolar protein sorting (VPS) genes (SNF7/VPS32, VPS4,...
Topics
- ATP-Binding Cassette Transporters
- Amino Acid Sequence
- Biological Transport, Active
- Carboxypeptidases
- Carrier Proteins
- Cathepsin A
- Endosomal Sorting Complexes Required for Transport
- Endosomes
- Fungal Proteins
- Gene Deletion
- Genes, Fungal
- Glycoproteins
- Membrane Proteins