Article
Stathmin 1 and p16(INK4A) are sensitive adjunct biomarkers for serous tubal intraepithelial carcinoma.
Gynecologic oncology - 1 Oct 2015
Novak Marián, Lester Jenny, Karst Alison M, Parkash Vinita, Hirsch Michelle S, Crum Christopher P, Karlan Beth Y, Drapkin Ronny
Abstract excerpt
OBJECTIVE: To credential Stathmin 1 (STMN1) and p16(INK4A) (p16) as adjunct markers for the diagnosis of serous tubal intraepithelial carcinoma (STIC), and to compare STMN1 and p16 expression in p53-positive and p53-negative STIC and invasive high-grade serous carcinoma (HGSC). METHODS: Immunohistochemistry (IHC) was used to examine STMN1 and p16 expression in fallopian tube specimens (n=31) containing...
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