Article
Advances in the recognition of tubal intraepithelial carcinoma: applications to cancer screening and the pathogenesis of ovarian cancer.
Advances in anatomic pathology - 1 Jan 2006
Lee Yonghee, Medeiros Fabiola, Kindelberger David, Callahan Michael J, Muto Michael G, Crum Christopher P
Abstract excerpt
Prophylactic salpingo-oophorectomies from women with BRCA mutations (BRCA+) have identified the tube as a frequent site of early pelvic serous carcinoma (tubal intraepithelial carcinoma [TIC]). These observations have implications for both the early recognition of pelvic serous carcinoma in susceptible women and determining the ultimate site of origin for pelvic serous carcinomas. Moreover, the unique pathology...
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