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Article

LEF1 is preferentially expressed in the tubal-peritoneal junctions and is a reliable marker of tubal intraepithelial lesions.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2017

Schmoeckel Elisa, Odai-Afotey Ashley A, Schleißheimer Michael, Rottmann Miriam, Flesken-Nikitin Andrea, Ellenson Lora H, Kirchner Thomas, Mayr Doris, Nikitin Alexander Yu

Abstract excerpt

Recently it has been reported that serous tubal intraepithelial carcinoma (STIC), the likely precursor of ovarian/extra-uterine high-grade serous carcinoma, are frequently located in the vicinity of tubal-peritoneal junctions, consistent with the cancer-prone features of many epithelial transitional regions. To test if p53 (aka TP53)-signatures and secretory cell outgrowths (SCOUTs) also localize to...

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Identifiers

PMID: 28664938
DOI: 10.1038/modpathol.2017.53
PMCID: PMC5604248

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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