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Article

High-grade serous ovarian carcinoma with a sertoliform pattern associated with BRCA mutation: a clinicopathological and molecular analysis.

Virchows Archiv : an international journal of pathology - 1 Dec 2023

Travaglino Antonio, Santoro Angela, Arciuolo Damiano, Raffone Antonio, Scaglione Giulia, D'Alessandris Nicoletta, Valente Michele, Sfregola Stefania, Fulgione Caterina, Onori Maria Elisabetta, Minucci Angelo, Zannoni Gian Franco

Abstract excerpt

Herein, we report a clinicopathological and molecular analysis of a case of tubo-ovarian high-grade serous carcinoma (HGSC) with a sertoliform pattern. A 45-year-old woman underwent surgery due to an advanced bilateral adnexal carcinoma with peritoneal and appendiceal metastases. Histological examination revealed an HGSC exhibiting a distinct sertoliform component. Such component showed diffuse PAX8, p53...

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PMID: 37166561
DOI: 10.1007/s00428-023-03556-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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