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Article

Contemporary Considerations for Constructing a Genetic Risk Score: An Empirical Approach.

Genetic epidemiology - 1 Sept 2015

Goldstein Benjamin A, Yang Lingyao, Salfati Elias, Assimes Themistoclies L

Abstract excerpt

Genetic risk scores are an increasingly popular tool for summarizing the cumulative risk of a set of Single Nucleotide Polymorphisms (SNPs) with disease. Typically only the set of the SNPs that have reached genome-wide significance compose these scores. However recent work suggests that including additional SNPs may aid risk assessment. In this paper, we used the Atherosclerosis Risk in Communities (ARIC) Study...

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Source

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Identifiers

PMID: 26198599
DOI: 10.1002/gepi.21912
PMCID: PMC4543537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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