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Article

Using a genetic risk score to calculate the optimal age for an individual to undergo coronary artery calcium screening.

Journal of cardiovascular computed tomography - 1 Jan 2019

Severance Lauren M, Contijoch Francisco J, Carter Hannah, Fan Chun C, Seibert Tyler M, Dale Anders M, McVeigh Elliot R

Abstract excerpt

BACKGROUND: Genetic risk scores (GRSs) have been associated with CHD events and coronary artery calcium (CAC). We sought to evaluate the ability of a GRS to improve CAC as a screening test. METHODS: Using the results of the most recent genome-wide association studies, we calculated a GRS in 6660 individuals from the Multi-Ethnic Study of Atherosclerosis and used it to determine the optimal age for an individual...

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Source

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Identifiers

PMID: 31104941
DOI: 10.1016/j.jcct.2019.05.005
PMCID: PMC6801022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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