Article
The mouse wellhaarig (we) mutations result from defects in epidermal-type transglutaminase 3 (Tgm3).
Molecular genetics and metabolism - 1 Nov 2015
Brennan Brett M, Huynh Minh T, Rabah Mohammed A, Shaw Hailie E, Bisaillon Jason J, Radden Legairre A, Nguyen Tu V, King Thomas R
Abstract excerpt
The recessive wellhaarig (we) mutations, named for the wavy coat and curly whiskers they generate in homozygotes, have previously been mapped on mouse Chromosome 2. To further limit the possible location of the we locus, we crossed hybrid (C57BL/6×AKR)F1, we(4J)/+ females with AKR, we(4J)/we(4J) mutant males to create a large backcross family that was typed for various microsatellite markers and single-nucleotide...
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