[The mutant gene wellhaarig disturbs the differentiation of hair follicle cells in the mouse].

Abstract excerpt

First generation (G1) hairs in mice homozygous for the wellhaarig (we) gene are wavy and shorter than in normal mice; basal regions of the hairs are deformed. Follicles of G1 hairs in mid-dorsal region of 8-, 12- and 16-days old we/we mice were examined. Huxley cells of the inner root sheath (IRS) in apical region of hair follicles appeared to be hypertrophied. Cytoplasm of these cells was not stained by basic...

Topics

• Aging
• Animals
• Cell Differentiation
• Genes
• Genotype
• Hair
• Homozygote
• Mice
• Mice, Inbred C57BL
• Mice, Mutant Strains
• Mutation
• Staining and Labeling