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Article

Epidermal transglutaminase (TGase 3) is required for proper hair development, but not the formation of the epidermal barrier.

PloS one - 1 Jan 2012

John Susan, Thiebach Lars, Frie Christian, Mokkapati Sharada, Bechtel Manuela, Nischt Roswitha, Rosser-Davies Sally, Paulsson Mats, Smyth Neil

Abstract excerpt

Transglutaminases (TGase), a family of cross-linking enzymes present in most cell types, are important in events as diverse as cell-signaling and matrix stabilization. Transglutaminase 1 is crucial in developing the epidermal barrier, however the skin also contains other family members, in partic...

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Identifiers

PMID: 22496784
DOI: 10.1371/journal.pone.0034252
PMCID: PMC3319564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22496784-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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